Monday 13 October
|
2:00PM
- 4:00PM |
Next
Generation Sequencing (NGS) Interest Group |
|
5:00PM
- 6:30PM |
Jean-Pierre
Issa: New horizons in cancer research and therapy |
Tuesday 14 October
|
9:15AM
- 12:15PM |
Bus
Departure
|
|
1:00PM
- 2:00PM |
Lunch |
|
2:00PM
- 2:15PM |
Official
Welcome from the Committee |
|
2:15PM
- 3:45PM |
Session
1a: Overview Cancer Epigenetics 1 |
|
|
Jean-Pierre
Issa: The cancer methylome
abs#001 |
|
|
Sam
El-Osta: Histone
Modification abs#002 |
|
3:45PM
- 4:15PM |
Afternoon
Tea |
|
4:15PM
- 5:45PM |
Session
1b: Overview Cancer Epigenetics 2 |
|
|
Frank
Lyko: Development of DNMT inhibitors for epigenetic
cancer therapy abs#003 |
|
|
Emma
Whitelaw: Epigenetic reprogramming and cancer abs#004 |
|
|
Marnie Blewitt: SmcHD1 is a
novel chromatin protein with a critical role in X inactivation
abs#005 |
|
6:15PM
- 7:45PM |
Dinner |
|
8:00PM
- 10:00PM |
Session
2: Hot Topics
|
|
|
Philippe
Collas: MicroChIP:
Scaling down chromatin immunoprecipitation assays
for small cell numbers and biopsies abs#006 |
|
|
Romain Lambrot: Histone methylation and gene
regulation in testicular cancer. abs#007 |
|
|
Ernst-Jan
Geutjes: A functional genetic screen identifies the
H3K4 demethylase Jarid1b as a regulator of a
senescence-like arrest. abs#008 |
|
|
|
|
|
Emma
Baker: THE ROLE OF MBD1, HP1α, AND H3K9 METHYLATION IN MULTIDRUG
RESISTANCE 1 GENE TRANSCRIPTIONAL REGULATION IN CANCER abs#010 |
|
|
Nicholas
Wong: Is there a role for DNA methylation in
paediatric acute lymphoblastic leukaemia? abs#011 |
|
|
Marcel
Coolen: Concordant & Discordant DNA Methylation Patterns In Imprinted Regions Of Monozygotic
Twins Demonstrate The Impact Of The Genome On The Epigenome
abs#012 |
|
|
Wen Qui: Genome-wide mapping of gene promoter methylation in breast cancer abs#013 |
|
10:00PM
- 11:00PM |
Evening
Social and Poster Viewing |
|
|
Akinola Adisa: Polycomb Group (PcG) genes:
Understanding their contributions to drug resistance in lymphoma
abs#051 |
|
|
Saul
Bert: Demethylation of an upstream promoter results
in activation of the macrophage colony-stimulating factor receptor (CSF1-R)
in human breast cancer. abs#052 |
|
|
Vanessa
BONAZZI: Identification of candidate tumour suppressor genes inactivated by
promoter methylation in melanoma cell lines
abs#053 |
|
|
Michael
Bots: Apaf-1 and caspase-9 are dispensable for HDACi-induced
cell death of B cell lymphoma abs#054 |
|
|
Ida
Candiloro: Rapid analysis of heterogeneously methylated DNA using digital Methylation
Sensitive - High Resolution Melting. abs#055 |
|
|
Brian
Gloss: Epigenetically silenced genes in ovarian cancer unmasked by
pharmacological reactivation and transcript profiling abs#056 |
|
|
Katie
Huang: DNA methylation profile of phyllodes and fibroadenoma
breast tumours abs#057 |
|
|
Toby
Hulf: IDENTIFICATION OF EPIGENETICALLY DEREGULATED
MICRORNAS IN PROSTATE CANCER abs#058 |
|
|
Kevin
Knower: Epigenetic regulation of local estrogen
biosynthesis in human breast adipose fibroblast cells abs#059 |
|
|
Lara
Lipton: Epigenetic change in colorectal cancer: how representative are ‘CIMP'
markers? abs#060 |
|
|
Thomas
Mikeska: MethMarker:
Design of DNA methylation assays and optimisation
for use as clinical biomarkers abs#061 |
|
|
Céline Montavon:
IDENTIFICATION OF METHYLATED GENES IN HIGH GRADE SEROUS OVARIAN CANCER
abs#062 |
|
|
Andrea
Newbold: Assessing the molecular mechanisms of HDACi-induced apoptosis in the absence of p21WAF1/CIP1.
abs#063 |
|
|
Rebecca
Ormsby: The effect of low dose radiation on global
genomic methylation levels abs#064 |
|
|
Michael
Raynor: DNA methylation
profiling of peripheral blood mononuclear cells by Sensitive Melting Analysis
after Real Time - Methylation Specific PCR
(SMART-MSP) reveals low level methylation of breast
cancer associated genes. abs#065 |
|
|
Melanie
Rich: DNA methylation markers in childhood acute
lymphoblastic leukaemia abs#066 |
|
|
Nezaket Turkel:
Characterization of a Novel Oncogene in Drosophila
abs#067 |
|
|
Erik
Wiklund: Epigenetic de-regulation of microRNAs in bladder cancer abs#068 |
|
|
Posters
can remain on display throughout the meeting |
Wednesday 15 October
|
7:00AM
- 8:15AM |
Breakfast |
|
8:30AM
- 10:15AM |
Session
3a: Genome Wide Epigenetic Analysis 1 |
|
|
John
Greally: The unexpected relationship of cytosine methylation with gene transcription. abs#014 |
|
|
Mathias
Ehrich: Epigenetic target identification
abs#015 |
|
|
Jeffrey
Jeddeloh: The Comprehensive Epigenome:
Arrays, Sequence Capture and 454 Bisulphite Sequencing abs#016 |
|
10:15AM
- 10:45AM |
Morning
Tea |
|
10:45AM
- 12:45AM |
Session
3b: Genome Wide Epigenetic Analysis 2 |
|
|
John
Edwards: Whole genome methylation profiles of
breast cancer abs#017 |
|
|
Steven
Jones: Histone Modification and Genetic Regulatory
Control abs#018 |
|
|
Susan
Clark: High resolution integrative epigenomics
identifies and characterizes regions of long range epigenetic silencing
(LRES) in prostate cancer abs#019 |
|
12:45PM
- 1:30PM |
Lunch |
|
1:30PM
- 5:30PM |
Free
time An
optional guided ranger walk will commence from the ranger station for those
who sign up first at 2:30pm |
|
5:30PM
- 7:00PM |
Session
4: Epigenetic therapy |
|
|
Jean-Pierre
Issa: Hypomethylation
therapy abs#020 |
|
|
Ricky
Johnstone: Enhancing the apoptotic and therapeutic anti-cancer effects of histone deacetylase
inhibitors. abs#021 |
|
|
Miles
Prince: Clinical experience with histone deacetylase inhibitors in T cell lymphomas, Hodgkin lymphoma,
myeloid malignancies and multiple myeloma. abs#022 |
|
7:00PM
- 8:00PM |
Dinner |
|
8:15PM
- 9:30PM |
Session
5: Epigenetic predisposition to Cancer |
|
|
Megan
Hitchins: Epimutations in
cancer syndromes abs#023 |
|
|
Alex
Dobrovic: Somatic methylation
and cancer predisposition abs#024 |
|
|
Vicki
Whitehall: DNA methylation throughout the human colorectum is associated with age, region and pathology.
abs#025 |
|
9:30PM
- 11:00PM |
Evening
Social and Poster Viewing |
Thursday 16 October
|
7:00AM
- 8:15AM |
Breakfast |
|
8:30AM
- 10:30AM |
Session
6: Epigenetic Studies of Selected Tumours |
|
|
Toshikazu
Ushijima: Epigenetic field for gastric cancerization,
and its induction by Helicobacter pylori infection abs#026 |
|
|
Maya
Kansara: A screen for epigenetically silenced tumor suppressor genes in osteosarcoma
abs#027 |
|
|
Joanne
Young: Heterogeneity in hyperplastic polyposis may have a genetic basis. abs#028 |
|
|
John
Mariadason: A coordinated Sp1/Sp3-mediated
transcriptional response involving immediate-early gene induction drives HDACi-induced apoptosis in colon cancer cells.
abs#029 |
|
|
Elizabeth
Algar: Imprinted CDKN1C
is activated by histone deacetylase
inhibitors and restoration of SMARCB1
in rhabdoid tumor.
abs#030 |
|
10:30AM
- 11:00AM |
Morning
Tea |
|
11:00AM
- 12:30PM |
Session
7: Methylation as a biomarker |
|
|
Nancy
Kiviat: Clinical implications of epigenetics changes present in cervical cancer and cervical
cancer precursor lesions abs#030 |
|
|
Matt
Trau: Nanotechnology approaches to biomarkers
abs#031 |
|
|
James
Devaney: Epigenetic Remodelling Across 2q14.2
Provides a Prostate Specific Cancer Biomarker abs#032 |
|
|
Includes
Conference summation (Jean-Pierre Issa) and
Conference close (Alex Dobrovic and committee) |
|
1:00PM
- 2:00PM |
Lunch |
|
2:15PM
- 5:15PM |
Bus
departure for Peter Mac |
Friday 17 October
|
10:30AM
- 1:30PM |
Alternate
bus departure for PeterMac |